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Transferrin (TF) carries Fe 3+ in the bloodstream and transfers iron in cells through transferrin receptor 1 (TFCR1)

590 Diabetic retinopathy is also closely associated with DPN, with shared risk factors, such as poor glycemic control, hypertension, and dyslipidemia contributing to the development of both microvascular complications

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BI-1 (BAX-1 inhibitor), a pro-survival PCD gene involved in the regulation of PCD pathways, was shown to reduce ROS accumulation in vertebrates and to activate Nrf2, which is a transcription factor of various antioxidants, including glutathione reductase (42, 64)