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Moreover, the prophylactic mechanisms of SF (141 mg/kg/day for 2 weeks) have been shown to protect against LPS-induced prefrontal cortex-related recognition memory impairment in mice by improving recognition memory and reducing neuroinflammation, oxidative stress, neurodegeneration, A accumulation, and microglial activation (68)

Benefits will still be present but at a much-reduced rate to the abovementioned process

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Altered development of acute oxaliplatin-induced peripheral neuropathy was also reported in patients with single nucleotide polymorphisms (SNPs) in SCNA genes encoding the voltage-gated sodium channels, which are essential for the initiation and propagation of action potential in neurons