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Frey II, a pioneer in intranasal central nervous system (CNS) delivery and adjunct professor at the University of Minnesota, explained it perfectly: We proved you could noninvasively deliver stem cells to the brain from the nose

However, the chosen mutants impaired in ABC-type MRP transporters, oligopeptide transporters (OPTs) and -glutamyl transpeptidases (GGTs) did not exhibit a difference in root growth inhibition during AITC treatment compared to the WT

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For example, metformin has been shown to enhance autophagy and mitophagy, making it a potential candidate for neurodegenerative diseases