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Therefore, mitochondrial diseases can result from both maternally inherited mtDNA mutations and classical genetic mutations in nDNA (1)

Besides stopping the formation of melanin, another method to treat pigmentation would be to stop the transfer of the pigments (i.e

Collectively, our in vivo and in vitro findings are consistent with TMAO aggravating kidney fibrosis due to ERK1/2 hyperactivation synergistically, probably with activation of the TGF-1-mediated SMAD3 pathway causing a secondary hit in our disease model