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Sex- and suicide-specific alterations in the kynurenine pathway in the anterior cingulate cortex in major depression

Notably, IL-6 not only modulates hepcidin to affect the release of stored iron from ATMs and intestinal absorption, but also reduces transferrin expression and aggravates iron accumulation by promoting hepcidin production

We hypothesize that stimulating key regenerative pathways in transplanted hepatocytes using hepatocyte growth factor (HGF) and epidermal growth factor (EGF) and preconditioning the host liver with P21 expression to prevent host hepatocyte proliferation will improve survival, proliferation, and engraftment of PHHs and HLCs in an injured mouse liver