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Description

Fattima Al-Zahra GabarG

Ferroptosis is characterized by the toxic accumulation of lipid peroxides at the cell membrane (Dixon et al, 2012

In the context of brain injury, macrophages exert a pivotal role in the induction of the inflammatory response (Popovich et al., 1999)

GFA can act as a glutathione (GSH) carrier to catalyze the reaction of GSH and CH2O to form s-hydroxy-methylglutathione (HMG)[1], GS-FDH can catalyze the oxidation of HMG dehydrogenation to form s-formylglutathione, and FGH can regenerate GSH [2]