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Senescent cells are damaged cells that no longer divide but contribute to aging and chronic inflammation

Therefore, the 1 H NMR spectrum is a mixed spectrum of -glucose and -glucose, as shown in Figure 13

doi: 10.1084/jem.20161120 165 KleinewietfeldMManzelATitzeJKvakanHYosefNLinkerRAet al

The mechanism involves capsaicin acting on endothelial TRPV1, causing Ca 2+ influx, which subsequently promotes eNOS phosphorylation and increases NO, BH, and cyclic guanosine monophosphate (cGMP) levels, enhancing vasodilation