Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB dbco-maleimide At neutral pH

At neutral pH

The activities of SNAP-tag and H5 enzymes on BGSN3 are reasonable (IC50=17

TCO (trans-cyclooctene) is a strained alkene used in click chemistry for bioorthogonal reactions like iEDDA (inverse electron-demand Diels-Alder)

Product Name Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4) Synonyms CAS Number Related CAS Molecular Formula C48H77N9O18 Molecular Weight 1068

Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB dbco-maleimide At neutral pHSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine