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What is nicotine and other facts PMI Philip Morris International Nicotine vs. Cocaine: Which Substance is More Addictive? Nicotine is highly addictive, especially for teens. Nicotine can affect attention, mood, learning, and impulse control while the brain is still developing. Many vaping products contain high levels of nicotine, making it 5 Most Addictive Substances: The Science of Dependency
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