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10.1038/nature03260 30 DaiD.-F.RabinovitchP

Continuous use without breaks is not recommended

10.21769/BioProtoc.4369 Bio-protoc 144 TongY.SongF

As expected, PS-CHO@ATRA-SS-ATRA exhibited highest down-regulation of Sox2 , Nanog and Oct4 genes in all formulations, further confirming that the ALDH-activated nano-prodrug could effectively eliminate the CSC and reduce the CSC-enriched microenvironment