ghk cu mechanism of action hair growth Do topical copper peptides work for treating thinning and hair loss? While they are interesting there is just no data on how well these work, who they work best for and GHK-Cu for Hair Loss: Evidence,

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[8] The interaction is also route-dependent in a way that undercuts easy reasoning: the zinccopper antagonism operates largely at the intestinal absorptive step, so an injected copper load does not interact with oral zinc the way an oral copper load would

For a small, water-soluble copper peptide, absorption from that depot would be expected to be reasonably efficient, but the depot also gives local peptidases and the local copper environment a first opportunity to act on the molecule before it reaches the systemic circulation

Copper toxicity concerns are generally minimal with topical applications due to limited systemic absorption