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Iwilfin, an orally available inhibitor of ornithine decarboxylase, was approved based on the results of a single-arm study of children with HRNB who were initially treated with standard regimens, including immunotherapy

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Autophagy plays an important role in neuro-toxicity and neuronal death induced by hypoxia-ischemia

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However, B12 is unique: whilst it is water-soluble, the liver stores substantial reserves lasting several years

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