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Increases in serum ferritin and altered iron metabolism are known to occur with inflammation

10.1074/jbc.M115.700534 93

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In particular, they found that, in the absence of BMAL1, NF-B-driven transcription was upregulated by the core circadian protein CLOCK, whereas BMAL1 hindered the CLOCK-induced increase in the activation of NF-B-regulated genes 71