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IGF-1 elevation: Sustained GH elevation raises IGF-1

Even mild or subclinical thyroid dysfunction can have profound effects on conception, pregnancy outcomes, and postpartum recoveryyet it's often overlooked in conventional care

2019;25(3):43243e6

Periodontal EDS (pEDS) is characterized by severe and intractable periodontitis of early onset (childhood or adolescence), lack of attached gingiva, pretibial plaques, and family history of a first-degree relative who meets clinical criteria Cardiac-valvular EDS (cvEDS) is characterized by severe progressive cardiac-valvular problems (aortic valve, mitral valve), skin problems (hyperextensibility, atrophic scars, thin skin, easy bruising), and joint hypermobility (generalized or restricted to small joints)