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This structure receives the anterior branches of the second and third sacral nerves, forming the sacral plexus

emphasized that SPRA is characterized by plasma blast expansion, follicular helper T cell (Tfh) infiltration, and the formation of synovial tertiary lymphoid structures (TLS), whereas such adaptive immune markers are notably absent in OA and SNRA ( In summary, although both osteoarthritis and rheumatoid arthritis are associated with the immune system, their immunological mechanisms and treatment approaches differ significantly