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10.1017/S0007114515001300 20 Fontagn DicharryS.VronV.LarroquetL.GodinS.WischhusenP.AguirreP.et al (2020)

No one has looked at the adverse effects they might have on humans. Svensson said the lack of information on these peptides is also her biggest issue

After weight loss, the ECM is in a compromised state

These modifications result from direct ROS attack on amino acids (proline, arginine, lysine, threonine) or indirectly via reactive aldehydes from lipid peroxidation (MDA, 4-hydroxynonenal), or through reactions with reducing sugars and advanced glycation end-products (Pinzaru et al., 2023)