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Virchows triad reflects or consists of abnormal blood constituents, vessel wall abnormalities (endothelialitis), and abnormal blood flow [371], a set of coagulopathies leading to venous thrombosis, that also occur in AF [21,23,369,372,373,374,375,376,377,378,379,380], and indeed are common in both acute [381,382,383,384,385,386,387,388] and long [389,390,391] COVID (which, of course, are also characterised by fibrinaloid microclots)

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However, very high doses aren't more effective than moderate doses for most people