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Conducted in 1981, DSIP was administered as an intravenous infusion at 25 nmol/kg to six volunteers

Participants Patients clinically diagnosed with acne scars, who met the following inclusion criteria, were recruited for the study

Tesamorelin FDA-approved for HIV-associated lipodystrophy, its used off-label to reduce abdominal fat and improve metabolic health

Petersburg, Russia Initial research in 1980s at Institute of Bioregulation and Gerontology Derived from studying pineal gland peptides and aging Over 40 years of Russian research (but limited Western studies) Inspired by observation that pineal gland function declines with age Why developed: Soviet/Russian focus on longevity research Searching for ways to extend healthy lifespan Understanding cellular aging mechanisms Pineal gland's role in aging and circadian rhythms Goal: Create synthetic peptide mimicking natural bioregulators Epithalon vs epithalamin: Epithalamin: Natural polypeptide complex from pineal glands (bovine) Epithalon: Synthetic tetrapeptide mimicking epithalamin's active component Epithalon more practical (synthetic production, consistent quality) Both target similar anti-aging pathways Learn peptide fundamentals and how peptides work at SeekPeptides to understand Epithalon's unique mechanisms