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doi:10.1073/pnas.95.14.8268

Research has shown that doses as low as 250 mg to 500 mg can have a measurable impact on skin properties over time

All-trans retinoic acid enhances the cytotoxic effect of decitabine on myelodysplastic syndromes and acute myeloid leukaemia by activating the RAR-Nrf2 complex