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Nevertheless, IGF-I mRNA abundance is reduced in the brain of hypophysectomized rats and, intracerebral infusion of GH restores IGF-I mRNA to 80% of normal levels[70], which points out that GH has a clear role in modulating brain IGF-I

66 INCORPORATING ADVANCE CARE PLANNING IN ADULTS WITH DECOMPENSATED CIRRHOSIS AT LIVER TRANSPLANT CENTERS: A NURSING-LED EDUCATIONAL INITIATIVE Janet Gripshover 1,2 , Rita DAoust 1 , Deborah Baker 1 and Arpan Arun Patel 3 , (1)Johns Hopkins University, (2)University of California Los Angeles, (3)Greater Los Angeles VA Healthcare System Background: Clinician inexperience with advanced care planning (ACP) is a barrier to patient-centered care for adults with decompensated cirrhosis (DC) at liver transplant centers

198 However, some studies suggest that aging immune responses may have a suppressive effect on cancer