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This suggests that dosage, formulation, and patient subtype may affect the therapeutic efficacy of CoQ 10 , and further investigations are warranted

Beyond weight loss, early exploratory data suggest potential benefits including: Reductions in HbA1c (a marker of blood sugar control) in people with type 2 diabetes Improvements in lipid profiles (cholesterol and triglycerides) Reductions in liver fat, which may be relevant for metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD), though these findings are preliminary Possible cardiovascular benefits

387 Pegloticase, a recombinant urate oxidase conjugated to polyethylene glycol (PEG), has been introduced to reduce immunogenicity and extend the half-life of rasburicase

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