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These amenable properties demonstrated for the small molecules led us to conduct a proof-of-concept in vivo study in diet-induced obese mice to test the hypothesis that the most potent inhibitor when administered systemically, would reverse obesity by causing substantial loss of body weight and adiposity without causing any observable adverse effects

It acts as a preservative, inhibiting bacterial growth after the vial has been opened and punctured multiple times with a syringe

Green R, Allen LH, Bjrke-Monsen AL, Brito A, Guant JL, Miller JW, et al Vitamin B12 deficiency Nat Rev Dis Primers

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