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31 Detoxification Dysfunction The role of xenobiotic metabolizing enzymes (XMEs) in the disease etiology of PD has been under investigation by numerous researchers for the last two decades

In contrast, compounds with extremely low LD 50 values (e.g., azadirachtin, celangulin, and isothiocyanates) exhibit high intrinsic potency but may be limited by formulation and application constraints

Thankamony A, Capalbo D, Marcovecchio ML, Sleigh A, Jrgensen SW, Hill NR, Mooslehner K, Yeo GSH, Bluck L, Juul A, Vaag A, Dunger DB

But since tanning agents such as erythrulose are now associated with skin aging 4 , its likely clear why you dont want to use oxidized vitamin C on your skin