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Immunofluorescence analysis using the mitochondrial marker TOM20 revealed that AR inhibition fully rescued the mitochondrial phenotype in SORD-deficient fibroblasts ( Figure 6A )

For example, while epidemiological studies provide information on the increased risk and incidence of lung cancer following exposure to radon and tobacco smoke, other unstudied stressors (physical, chemical, or even social) can influence the outcomes of these studies, as can the data collection methodology (150, 151)

These DML are located at predicted transcription factor binding sites (TFBS) according to the JASPAR CORE 2022 database (Fig