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Enhances performance and endurance.

doi: 10.1016/j.domaniend.2011.06.002 13 KleivelandC

It is a profound, cellular-level energy crisis

ZO proteins also known as tight junction protein (TJP), can interact directly with occludin and claudins via their PDZ domains, whereas their C-terminus can associate with actin, thus providing a direct link with the cytoskeleton