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Description

Hydroperoxides (ROOH) Hydroperoxides are unstable compounds formed via lipid (LOOH), protein (POOH), and DNA oxidation, originating primarily from three hepatic sources: (1) electron leakage from the mitochondrial electron transport chain (particularly Complex I/III), (2) ROS-generating activity of CYP2E1, and (3) the NOX enzyme family (predominantly NOX4)

Cochrane Database Syst Rev (2014) (3):Cd005228

For most older adults with mild-to-moderate deficiency, no, high-dose oral or sublingual B12 corrects deficiency as well as injections in randomized trials