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It is reported that inducing ferroptosis by inhibiting Nrf2/Keap1/xCT signaling readily sensitized cisplatin-resistant cells to cisplatin in gastric cancer (Fu et al., 2021)

*Correspondence: Shuwen Liu, [email protected] Peck, [email protected] This article was submitted to Food Microbiology, a section of the journal Frontiers in Microbiology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

While this is a single case and cannot establish efficacy on its own, it adds to the body of evidence suggesting BPC-157's potential in autoimmune gastrointestinal conditions

Since post-translational control mechanisms have been proposed to participate in the regulation of rapid oxidative activation of GCL [15, 60], inducing ferroptosis by targeting PTMs might be a promising therapeutic strategy for cancer treatment