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When racemic albuterol was administered either intravenously or via inhalation after oral charcoal administration, there was a 3- to 4-fold difference in the area under the concentration-time curves between the (R)- and (S)-albuterol enantiomers, with (S)-albuterol concentrations being consistently higher

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Additionally, microbes produce or consume numerous metabolites amino acids, bile acids, choline derivatives, vitamins which can enter circulation and act on distant organs including the brain [48]