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Yamamoto J, Imai J, Izumi T, Takahashi H, Kawana Y, Takahashi K, et al

PMID: 36624452 J Transl Med Metformin counteracts stimulatory effects induced by insulin in primary breast cancer cells

NF-B signaling pathway The NF-B pathway is a master regulator of inflammation, orchestrating the transcription of numerous pro-inflammatory cytokines and mediators [129,130,131]

The purity of lutein extracted was determined to be 90% using a spectrophotometer, HPLC, TLC-mass, and Proton and Carbon NMR, as previously described 48