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SKU: 89308336465
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DOI: 10.1146/annurev.bi.55.070186.005303 Hollenberg, S.M., Weinberger, C., Ong, E.S., Cerelli, G., Oro, A., Lebo, R., Thompson, E.B., Rosenfeld, M.G., Evans, R.M

Halpin SJ, Hamlin PJ, Greer DP, Warren L, Ford AC

Abatacept (ABT) is a co-stimulation inhibitor that can bind to CD80 and CD86, preventing CD28-mediated T cell activation by blocking costimulatory signaling