glutathione s transferase inhibitor transferases as mediators of signaling pathways involved in cell proliferation and cell death Inhibitors of glutathione S-transferases as

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Abstract Ulcerative colitis (UC) is a non-specific inflammatory bowel disease that causes ulcers and erosions in the colonic mucosa and becomes chronic with cycles of amelioration and exacerbation

Blending Science with Nature: We combine evidence-based medicine with naturopathic wisdom to support deep, lasting healing

Through experimental methods such as molecular docking, CESTA, and non-targeted metabolomics, we found that SAC can act on the Keap1/Nrf2/GPX4 signaling axis and regulate glutathione metabolism, effectively inhibiting ferroptosis and oxidative damage in colonic epithelial cells, thereby alleviating UC