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344 Antidepressants ATs used in migraine prevention include the tricyclic antidepressants (TCAs) amitriptyline and nortriptyline and the serotonin-norepinephrine reuptake inhibitors (SNRIs) venlafaxine and duloxetine, with proposed MOAs involving modulation of neurotransmitters

Fransen E, Bonneux S, Corneveaux JJ, Schrauwen I, Di Berardino F, White CH, Ohmen JD, Van de Heyning P, Ambrosetti U, Huentelman MJ, Van Camp G, Friedman RA

Thus, we provide a cell-active small molecule tool for oxidative pentose phosphate pathway inhibition, and use it to identify G6PD as a pharmacological target for modulating immune response

These developments underscore the need for future research focused on developing more selective and targeted copper ionophores for HF therapy