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However, because lysine residues are numerous on antibodies, the resulting conjugates can be heterogeneous (varying DAR), which may impact the overall pharmacokinetic stability and therapeutic index compared to site-specific conjugation methods

[ 100 ], who in 2000 showed that BPC 157 can serve as a potent antidepressant as measured by the Porsolt test (where peptide counteracts freezing)

No change in glucose tolerance was demonstrable on the fifth day of administration of monkey growth hormone." [84] The other study, published in 1958, was conducted on six people: the same subject as the Science paper

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