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Description

Aerosol Sci Technol 52:12191232

Parameters such as target print ratio (TPR), swing duration ratio (SWR), and the Limb Idleness Index (LII) were significantly altered over time, reflecting decreased loading and increased paw elevation time on the operated hindlimb

There are two approaches: dose reduction (lowering the amount per injection while maintaining frequency) and frequency reduction (maintaining dose but spacing injections further apart)