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101 On the one hand, autophagy plays an inhibitory role in the early stages of tumors by maintaining genome stability, removing damaged mitochondria, and inhibiting malignant transformation of cells

Normal endothelium

FR primarily is localized in the following tissues, such as: Reproductive tissues Immune system Hematopoietic tissues, such as thymus, spleen, and bone marrow Ovarian carcinoma, choriocarcinoma of the testis, and primary peritoneal carcinoma Originally, FRs were identified as a high-affinity soluble plasma folate-binding protein