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Higher overlap between iron deposition and lesion areas correlates with more severe damage to neurons and glial cells, resulting in widespread functional impairments (Wehn et al., 2021

At the same time, it reduces oxidative stress by supporting antioxidant pathways

Weyermann M, Rothenbacher D, Brenner H

Oxidative stress was assessed by quantifying thiobarbituric acid (TBA) reactivity as malondialdehyde (MDA) equivalents and by determining the NO levels in the colon tissue