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1.5 g of Cinnamon treatment for 8 weeks to PCOS patients significantly inhibited serum fasting blood glucose, insulin, HOMA-IR, total cholesterol and LDL-cholesterol, but increased HDL-cholesterol compared to placebo group [121]

Side effects are uncommon and typically limited to mild injection site reactions

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OVERALL CONCLUSIONS 5-Amino-1MQ enables precise interrogation of NNMTs role at the crossroads of NAD metabolism, one-carbon biochemistry, and adipocyte energetics