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Both compounds shift the body toward a catabolic state

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Overgrowth of bacteria: Some people develop vitamin B 12 deficiency as a result of conditions that slow the movement of food through the intestines (diabetes, scleroderma, strictures, diverticula), allowing intestinal bacteria to multiply and overgrow in the upper part of the small intestine

Copper is an essential cofactor for a range of enzymes involved in follicle function, including lysyl oxidase (involved in extracellular matrix cross-linking) and superoxide dismutase (an antioxidant enzyme expressed within the follicle)