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These cells are essential to maintain blood vessel integrity and blood fluidity [2]

The stained slides examined were under a light microscope (B-500 Ti-5 by Optika) by two histopathologists blinded to the study objectives or groups

Meanwhile, it is urgent to develop cartilage-targeted delivery systems to enhance the bioavailability of drugs in the joint cavity and their specific binding ability to chondrocytes, while avoiding potential interference with the homeostasis of the gut microbiota