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However, currently available medications all cause significant adverse effects [9,13,14]

Given previous observations of GSH depletion in severe asthma (8688), a disorder necessitating treatment with high doses of corticosteroids, additional investigations of the effect of corticosteroids on GSH/GSSG redox balance are needed

This proteomic insight paves the way for developing personalized, EV-based strategies, such as loading EVs with therapeutic proteins or engineering them for targeted drug delivery, thereby significantly advancing treatment precision and personalization

Then 100 M of the sample was used for the derivatisation, as described above, without the addition of an internal standard