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As shown previously, the interaction with PMNs led to increased expression of PbSOD1 and PbSOD3 , both in the presenceto a greater extentand absence of DPI (S6 Fig)

Encouraging results have been reported in the treatment of pancreatic cancer using intravenous ALA (300 to 600 mg twice weekly) plus low-dose oral naltrexone (4.5 mg once daily) [143]

Antibiotics (10,000 U/ml penicillin, 10 mg/ml streptomycin), PBS, and Trypsin EDTA solution C (0.05% trypsin0.02% EDTA) were obtained from Biological Industries (Kibbutz Beit Haemet, Israel), and fetal bovine serum (FBS) from Invitrogen (Carlsbad, CA, USA)

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