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World Journal of Diabetes : Association Between Metformin and Vitamin B12 Deficiency in Patients With Type 2 Diabetes World Journal of Diabetes : Long-Term Metformin Therapy and Vitamin B12 Deficiency: An Association to Bear in Mind Diabetes, Obesity & Metabolism : Metformin-Induced Vitamin B12 Deficiency Can Cause or Worsen Distal Symmetrical, Autonomic and Cardiac Neuropathy in the Patient With Diabetes U.S

Horm Res 40 : 6267 Mauras N (1995) Combined recombinant human growth hormone and recombinant human insulin-like growth factor I: lack of synergy on whole body protein anabolism in normally fed subjects

But research consistently shows that neurological and metabolic dysfunction begins at levels below 400500 pg/mL in many individuals

The strongest data comes from Harshini Neelakantan, Stan Watowich, and colleagues at the University of Texas Medical Branch (UTMB)