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Neuropsychopharmacol 38, 2338

Transformingly, the original figure was transformed to be compared with the found results, demonstrated by total BACE1 expression of mBCEC from AST/Bex-treated 3xTg AD mice, that are lower than the BACE1 expression level in 3xTg AD mice and non-transgenic

Among reviewed studies, the following SLC transporters have been targeted for delivery of various drugs to the brain: organic cation/carnitine transporter 2 (OCTN2), glucose transporters (GLUTs), LAT1, sodium-dependent vitamin C transporter 2 (SVCT2) and glutathione transporters (Tables II and III)

Cell culture and peptide handling The HCC line HepG2 (American Type Culture Collection (ATCC) Manassas, VA, USA) was maintained in Dulbeccos modified Eagles media (DMEM) with 4.5 g/l glucose (Corning, Corning, NY), 10% fetal bovine serum (Corning), and 100 U/ml penicillin and streptomycin (Gibco)