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Regulation of Nrf2 by mitochondrial reactive oxygen species in physiology and pathology

Grings M, Moura AP, Parmeggiani B et al (2017) Bezafibrate prevents mitochondrial dysfunction, antioxidant system disturbance, glial reactivity and neuronal damage induced by sulfite administration in striatum of rats: implications for a possible therapeutic strategy for sulfite oxidase deficiency

This two-pronged assault on a host selenoprotein suggests that the virus must benefit significantly by the disruption of SELENOF activity

Ferroptosis Ferroptosis, an iron-dependent form of cell death, is primarily triggered by the accumulation of toxic lipids, especially lipid hydroperoxides [77]