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doi: 10.30574/gscarr.2024.18.3.0096 92

These data suggested that GSH has very important functions in morphogenesis by promoting the formation of stable capsid precursors and of the mature virus

However, FRDA iPSC-based cells had functional mitochondria and functional secretion of glucose-induced insulin ( Therapeutic solutions for Friedreichs ataxia with the help of induced pluripotent stem cell-based technologies Heterochromatin formation around the FXN gene is the major reason for the downregulation of the FXN gene in FRDA ( FXN gene ( in vitro models ( FXN levels along with a decrease in oxidative stress response ( FXN reporter system revealed HDAC inhibitors as the only compounds that could upregulate FXN levels ( Recent advances in genome editing enabled the correction of expanded alleles in FRDA