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& Falasca, M

Results from the trial revealed that the mean maximum daily dose of 1457 mg (27.1 mg/kg) with a mean final serum valproate concentration of 80 mcg/ml was attained in this clinical trial

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Furthermore, given the fact that danger signals often change multiple times in lipid metabolism, developing more potent activators/inhibitors that target multiple FAO signaling pathways, including the CPT system or combined with other anti-inflammatory/antitumor therapeutics, may facilitate translation of this promising strategy into clinical application