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6 Summary Owing to their strategic anatomical positioning, diverse receptor repertoire, and potent secretory capability, MCs function as a pivotal nexus within the vitiligo lesion microenvironment, integrating signals across the neural, endocrine, and immune axes ( Figure 4 )

The coating process itself may alter the nanoparticles size, stability, or morphology, requiring precise optimization for each new formulation [45]

However, they might pose a higher risk of side effects and are relatively more invasive

[34] Management of GHB dependence involves considering the person's age, comorbidity and the pharmacological pathways of GHB