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Methotrexate slows down the progression [of inflammation] so it reduces the destruction of the joints. 2

and Looper, K.J., 2009

The chemical formula of PLP is C8H10NO6P

While Zn supplementation has shown potential to improve outcomes in some cases (Table 1), variability in results highlights the need for further mechanistic understanding of the reciprocal mechanistic regulation between Zn metabolism and IBD