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Succinic dehydrogenase subunit A deficiency (OMIM #252011) Succinic dehydrogenase subunit A (SDHA), a flavoprotein with FAD as cofactor, is a nuclear encoded and catalytic subunit of Complex II (succinate dehydrogenase) which oxidizes succinate to fumarate in the Krebs cycle and transfers electrons to ubiquinone in the mitochondrial electron transport chain [115]

Size exclusion chromatography (gel filtration) separates proteins by their effective hydrodynamic radius the Stokes radius rather than strictly by molecular weight, because elongated proteins experience more frictional resistance than compact globular proteins of equal mass

Uric acid is associated with inflammatory biomarkers and induces inflammation via activating the NF- B signaling pathway in HepG2 cells