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Safety animal and some human data profiles generally look good, but clinical fertility trials are sparse

Proc Natl Acad Sci U S A 81:935939 Roberts CT Jr, Lasky SR, Lowe WL Jr, Seaman WT, LeRoith D (1987) Molecular cloning of rat insulin-like growth factor I complementary deoxyribonucleic acids: differential messenger ribonucleic acid processing and regulation by growth hormone in extrahepatic tissues